Evidence against singlet oxygen formation by sonolysis of aqueous oxygen-saturated solutions of Hematoporphyrin and Rose Bengal
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منابع مشابه
Role of Caspases and Reactive Oxygen Species in Rose Bengal-Induced Toxicity in Melanoma Cells
Objective We have previously shown that Rose Bengal (RB) alone, not as a photosensitiser, could induce apoptotic- and non-apoptotic cell death in different melanoma cell lines. To clarify RB-induced toxicity mechanisms, role of caspases and reactive oxygen specious (ROS) were studied in melanoma cells. Material and Methods Human melanoma cell lines, Me 4405 and Sk-Mel-28 were cultured in DM...
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Singlet oxygen is a highly reactive form of molecular oxygen that is harmful to biological systems. Here, the role of three iron-containing superoxide dismutase (sodB) genes is clearly shown in protecting Agrobacterium tumefaciens against singlet oxygen toxicity. A sodBI mutant was more sensitive to singlet oxygen than both wild-type bacteria and a double sodBII-sodBIII mutant strain. Moreover,...
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The photoreactivity of 4-thiothymidine (S(4)TdR) under visible light in the presence of Rose Bengal (RB), acting as a photosensitizer, was investigated in aqueous solutions at pH 7 and 12, using UV-vis, FTIR-ATR and (1)H-NMR spectroscopic techniques, time resolved absorption spectroscopy and electrospray ionization mass spectrometry (ESI-MS). Evidence for the generation of thymidine (TdR) as th...
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In a study of aerobically perfused rat hearts, the in situ photoactivation (530-590 nm) of rose bengal (a process that leads to the production of singlet oxygen and superoxide) has been shown to lead to the rapid development of electrocardiographic abnormalities and arrhythmias. With rose bengal concentrations of 1,000, 500, 250, 100, and 50 nmol/l (n = 6/group), photoactivation (3,600 lx) led ...
متن کاملFormation of singlet oxygen by the myeloperoxidase-mediated antimicrobial system.
Myeloperoxidase. H,O,, and a halide form a potent antimicrobial system which is operative in the polymorphonuclear leukocyte (PMN). The formation of singlet oxygen (‘0,) by this system is suggested by (a) the conversion of 2,5diphenylfuran to its specific singlet oxygen product cisdibenzoylethylene (cis-DBE); (b) the inhibition of this reaction by the ‘0, quenchers p-carotene, bilirubin, histid...
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ژورنال
عنوان ژورنال: Ultrasonics Sonochemistry
سال: 2000
ISSN: 1350-4177
DOI: 10.1016/s1350-4177(99)00042-5